Study design
The THRIVE study is a 3-arm longitudinal randomised controlled trial which will rigorously evaluate the efficacy of two parenting interventions, Enhanced Triple P for Baby and Mellow Bumps by comparing them against the routine care provided to vulnerable women during pregnancy (care as usual). This is a multi-component study which will collect the following data:
• baseline and follow up quantitative survey data from vulnerable mothers
• video recordings of mother-child interaction
• in-depth qualitative interviews with mothers
• in-depth qualitative interviews with partners
• video/audio recordings of practitioners delivering the interventions
• audit questionnaires on intervention delivery from practitioners
• in-depth interviews with practitioners delivering the interventions
• in-depth interviews with the supervisors of practitioners
• in-depth interviews with referring health and social care practitioners
• analysis of routinely collected data
The trial will be conducted within a number of NHS approved locations within the NHS Greater Glasgow and Clyde and NHS Ayrshire and Arran Health Board areas. Visits will also be made to the woman’s homes for data collection.
Questionnaires
The severity of any psychological distress across 9 dimensions will be measured using the Brief Symptom Inventory (BSI-53).
Health status will be measured using European Quality of Life – 5 dimensions scale (EQ-5D-3L), a generic measure of health, required for the economic evaluation.
Hospital Anxiety and Depression Scale enhanced by the outwardly–directed irritability questions from the Adult Wellbeing Scale (HADS+I).
Karitane Parenting Confidence Scale will be used to measure the mothers’ experiences of being a parent.
An evaluation questionnaire will be completed by each mother after each support group.
Practitioners will complete post-session evaluation forms and questionnaires on their expectations and experiences of taking part.
Long-term outcomes will be assessed by collecting data that is collected routinely as infants grow. These will be collected from measures such as the Strengths and Difficulties Questionnaire (SDQ) and the Sure Start Language Measure.
Research Findings
Recruitment is now complete and results will be published once follow-up data collection is complete.
The THRIVE Team
The research is led by Dr. Marion Henderson, and involves researchers based at the University of Glasgow, Glasgow Caledonian University, the University of Aberdeen, the University of Manchester and the University of Newcastle.
You can contact the THRIVE team by telephone on 0800 389 2129 or by emailing thrive@sphsu.mrc.ac.uk.
Co-applicants
University of Glasgow
Co-applicants:
Prof. Daniel Wight
Dr. Katie Buston
Prof. Emma McIntosh
Dr. Kathleen Boyd
Dr. Alex McConnachie
Prof. Helen Minnis
Dr. John O’Dowd
Ms Ruth Dundas
Formally of Glasgow Caledonian University
Dr. Elizabeth McGee
University of Manchester
Dr. Anja Wittkowski
Prof. Rachel Calam (now retired)
University of Newcastle
Prof. James Law
University of Aberdeen
Prof. Phil Wilson
Dr. Lucy Thompson
Steering Group:
Prof. Rudi Dallos (Chair)
Dr. Linda De Caestecker
Dr. David Conway
Prof. Ruth Freeman
Prof. David Tappin
Mary Glasgow
Anne Clark
Matt Forde
Elaine Moore
Michelle Hamilton (lay member)
Publications
Buston K, O’Brien R, Wight D, Henderson M (2019) The reflective component of the Mellow Bumps parenting intervention: Implementation, engagement and mechanisms of change. PLoS ONE 14(4): e0215461. https://doi.org/10.1371/journal.pone.0215461